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Causes of Alzheimer's Disease

Scientists believe that a combination of genetic, lifestyle, and environmental factors influence when Alzheimer’s disease begins and how it progresses. 

Watch a video about how Alzheimer's changes the brain.

In the News


What Causes Alzheimer's Disease?

A combination of age-related brain changes, genetics, and factors related to health, environment, and lifestyle may play a role in the development and course of Alzheimer's disease. Get more information.
Genes in a cell, with one gene magnified to show chromosomes, and then one portion of the chromosome magnified to show the double helix of the D N A..

Assessing Risk for Alzheimer's Disease

A family health history can help you and your doctor know if Alzheimer's disease runs in your family. Learn about genetic and other risks for early- and late-onset Alzheimer's.
African-american family

Alzheimer's Disease Genetics Fact Sheet

Read about the genetics of Alzheimer's disease and related research. A genetic mutation can cause early-onset Alzheimer's. Genetic variants influence disease risk.
Cell with nucleus, 23 pairs of chromosomes, genes, DNA strand labeled

Alzheimer's Disease in People with Down Syndrome

Many, but not all, people with Down syndrome develop Alzheimer's disease when they get older. Learn about the connection between the two and how to participate in research studies exploring this relationship.
Middle aged adult with Down Syndrome