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Building 31, Room 5C27
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Bethesda, MD 20892
Phone: 301-496-1752
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  • SIRT1 repairs DNA but leads to age-related gene expression in mice
    May 12, 2009

    Scientists have found a mechanism involving the protein SIRT1 that links DNA damage with age-related changes in gene expression. The study in mice has striking parallels with findings from studies of a similar mechanism in yeast. Past...

  • Smallpox vaccine confers longtime immunity
    May 12, 2009

    The threat of smallpox resulting from bioterrorism has prompted a reassessment of the current population’s level of immunity. A recent study by researchers in the NIA’s Intramural Research Program shows that older adults who...

  • Bone remodeling protein works indirectly through gut
    May 12, 2009

    The protein Lrp5, long known to play a critical role in bone remodeling, appears to exert its effects through the gut, not directly through the bone, as previously thought, according to preclinical research published in Cell. The findings...

  • Hormone therapy linked to brain shrinkage
    May 12, 2009

    Two recent imaging studies shed light on how menopausal hormone therapy (MHT) may affect the brains of older women. Previous studies showed that MHT increased the likelihood that older women would have difficulty with thinking skills and...

  • cover of exercise guide
    Exercise for all older adults: NIA guide shows and tells
    May 1, 2009

    The NIA’s new exercise guide for older adults has something for everyone. Whether healthy, chronically ill, or disabled, most older people can be physically active. The newly updated guide shows them how. “A central goal of...

  • Researcher using computer in lab
    New drugs for Alzheimer's: NIA boosts translational research
    May 1, 2009

    Dr. Roberta Diaz Brinton of the University of Southern California (USC) in Los Angeles knew she needed to take the next step. Her studies showed that allopregnanolone, one of the most common steroids in the brain, boosted the brain...

  • recovery.gov logo
    Recovery Act funds stimulate aging research
    May 1, 2009

      The American Recovery and Reinvestment Act of 2009 (ARRA) was signed into law by President Obama on Feb. 17, 2009. The NIH will receive $10 billion in ARRA funds to be used in fiscal years (FY) 2009 and 2010. The NIA will...

  • Combination scanning yields better diagnosis of mild cognitive impairment
    April 15, 2009

    A combination of magnetic resonance imaging (MRI) and positron emission tomography (PET) can more accurately detect mild cognitive impairment (MCI) brain abnormalities in the early stages of their development than can either method used...

  • Familial Alzheimer's disease may provide biomarker model
    April 15, 2009

    Examination of people at risk for the rare familial form of AD may provide clues to how the disease develops in others—years before clinical symptoms appear, according to a recent study. The clues are levels of certain proteins found...

  • More tau protein in cerebrospinal fluid associated with earlier onset of Alzheimer's
    April 15, 2009

    People with increased levels of tau protein in their CSF develop late-onset AD at earlier ages than do others with the disease, according to a study by researchers at the Washington University School of Medicine in St. Louis. The levels of...

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